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Penile erection is a hemodynamic process based on the relaxation of smooth muscles of cavernous bodies and located in its arterioles. During sexual stimulation of the nerve endings of cavernous bodies released nitric oxide (N0), activating the enzyme guanylate cyclase, which leads to higher content in the cavernous bodies of cyclic guanosine monophosphate (cGMP). The result is relaxation of smooth muscles of cavernous bodies, which increases blood flow to the penis.


By blocking specific phosphodiesterase fifth type (PDE5), which participates in the cleavage of cGMP, Vardenafil, thus enhances the local action of endogenous nitric oxide (N0) in the cavernous bodies during sexual stimulation. This effect causes the ability of vardenafil to strengthen the response to sexual stimulation.
Indications for use: Levitra is for impotence in men. Impotence can be caused by various factors: age, medication, diabetes, high cholesterol and blood sugar levels, diseases of the bladder, depression, diseases, cardiovascular diseases and, finally, the relationship between the partners. With impotence (erectile dysfunction) in men does not occur normal erections necessary for sexual intercourse. It is important to know that Levitra (vardenafil) has no effect on sexual desire (libido), the activity of the sperm or the ability to fertilize an egg.

 

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