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Proscar - a synthetic compound 4-azasteroidnoe - preparation of a new class of specific inhibitors of 5-alpha reductase, an intracellular enzyme that converts testosterone into the more potent androgen - dihydrotestosterone. Finasteride has no affinity for androgen receptors. Prostate growth and subsequent development of adenomas depend on the conversion of testosterone to DHT within the prostate gland. As a result of inhibition of 5-alpha reductase inhibitors for 24 hours after ingestion of the drug there is a noticeable decrease in the concentration of dihydrotestosterone in the circulation and within the prostate gland. The drug causes a decrease in the size of enlarged prostate, improves urine flow and reduces the symptoms associated with BPH. Reduction of clinical manifestations of disease may require several months of treatment.